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Dedifferentiated liposarcoma
3 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Familial leiomyomatosis
1 OMIM reference -
1 associated gene
10 signs/symptoms
Dedifferentiated liposarcoma
Familial leiomyomatosis

CDK4
(UniProt - OMIM)
 FH
(UniProt - OMIM)
HMGA2
(UniProt - OMIM)
MDM2
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
MDM2
(0.63)
FH


Citations in the biomedical literature:


Dedifferentiated liposarcoma
CDK4 HMGA2 MDM2
Familial leiomyomatosis
FH



Dedifferentiated liposarcoma
Familial leiomyomatosis

Synonym(s):
- DDLS
Synonym(s):
- Familial leiomyomatosis with renal carcinoma
- Familial leiomyomatosis with renal cell cancer
- Familial multiple cutaneous leiomyomas
- HLRCC
- Hereditary leiomyomatosis
- Hereditary leiomyomatosis with renal carcinoma
- Hereditary leiomyomatosis with renal cell cancer
- Hereditary multiple cutaneous leiomyomas
- Multiple cutaneous and uterine leiomyomas
Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare oncologic disease
- Rare renal disease
- Rare skin disease
Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic
Epidemiological data:
Class of prevalence: unknown
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: autosomal dominant
External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
No MeSH references
Familial leiomyomatosis

Very frequent
- Autosomal dominant inheritance
- Muscle anomalies
- Skin tumors / lumps / epidermal cysts

Frequent
- Pruritus / itching

Occasional
- Cataract / lens opacification
- Esophageal neoplasm / tumor / carcinoma / cancer
- Kidney / renal neoplasm / tumor / carcinoma / cancer
- Megaesophagus / cardiospasm / congenital dilation of the esophagus / achalasia
- Uterus / uterine / cervix / endometrium neoplasm / tumor / carcinoma / cancer
- Vaginal / vulvar neoplasm / tumor / carcinoma / cancer


Dedifferentiated liposarcoma

(no data available)